Unlike normal Vasebreaker levels, you should not break vases from the far right to left in this level. Instead, the player should break vases from the sixth column back. Be sure to plant a Tall-nut in each lane to prevent Pogo Zombies from getting through. The other fifteen vases contain only plants and Jack-in-the-Box Zombies most of the time. Even if there are Pogo Zombies, you will still have a Tall-nut. However, there are fewer Tall-nuts than Pogo Zombies, so be sure to use Squashes on Pogo Zombies in the lanes without a Tall-nut.
Another Chain Reaction and its prequel are the only Vasebreaker levels that when a Jack-in-the-Box Zombie explodes, it can create an explosive chain reaction, which explains why these levels' names are Chain Reaction.
Another Chain Reaction is the only Vasebreaker level that has Pogo Zombie.